Northeast Missouri

Region · Missouri

Northeast Missouri

From you
Nearest airportIRK · 38 mi
On this page

Overview

Northeast region of Missouri.

Updated from Wikivoyage on 1 October 2026 · Something wrong or missing? Improve it on Wikivoyage

Plan your trip

Getting there

  • From you: to see whether to drive or fly, and how long it takes.
  • IRK Kirksville Regional Airport, Kirksville — 38 mi away. Directions
  • UIN Quincy Regional Airport Baldwin Field, Quincy — 52 mi away. Directions
  • STL St. Louis Lambert International Airport, St Louis — 112 mi away (major hub). Directions
Full “Get in” guide ↓

Sample 3-day trip

  1. Day 1: Hannibal — Mark Twain Boyhood Home & Museum, Rockcliffe Mansion, Mark Twain Cave Complex.
  2. Day 2: Mexico — Audrain County Courthouse, Ross House, Arthur Simmons Stables Historic District.
  3. Day 3: Kirksville — Thousand Hills State Park.

Built from the best-covered destinations in this region; open each for its own day plan.

Places in Northeast Missouri

Cities

  • Bowling Green — there is a sizable Amish community next to the town, which is worth an afternoon exploring
  • Hannibal — the boyhood home of author Mark Twain, and the setting for The Adventures of Tom Sawyer and Adventures of Huckleberry Finn; there are many sites in the city connected to Twain and his writings
  • Kirksville — home of Truman State University and A.T. Still University
  • Mexico — small town charm and urban style, with artsy boutiques and cultural offerings

Nearby

My experience

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